Cycloxydim

Cycloxydim is a herbicide, which could be used and applied on crops without any restrictions. In the EU (under CLP) its classification as reprotoxic is under discussion with a probabale outcome of "no classification".

Physico-chemical Properties

• Molecular weight: 325.5
• Physical form: Colourless, odourless crystals; ( tech., yellow beige crystals, with a weak aromatic odour; dark brown oil above m.p.).
• Density: 1.12 (20 °C); Melting point:c. 41 °C;
• Flash point: 119 °C ( tech.);
• Vapour pressure: <0.01 (20 °C);
• Henry constant 8.14×10-5 Pa m3 mol-1 ( calc.);
• Partition coefficient(n-octanol and water): logP c. 1.36 ( pH 7, 25 °C).; pKa:c. 4.17;
• Solubility: In water 40 mg/l (20 °C). In acetone, ethanol, dichloromethane, ethyl acetate, toluene >1000 (all in g/ kg, 20 °C). In n-hexane 29 g/ kg (20 °C).;
• Stability: Stable at room temperature for 1 y; unstable above 30 °C; decomposes c. 127 °C. DT50 in argon atmosphere at 20 000 lux (simulated sunlight, 15-20 °C) >192 h; in air at 80 000 lux (simulated sunlight, 20 °C).
• WATER SOLUBILITY: Tech: 0.0053 g/100g at 20°C.

Toxicology

• Oral: Acute oral LD50 for rats c. >5000 mg/ kg.
• Percutaneous: Acute percutaneous LD50 for rats >2000 mg/kg.
• Non-irritating to skin and eyes (rabbits).
• Inhalation: LC50 (4 h) for rats >5.28 mg/l.
• Phytotoxicity: Non-phytotoxic to all broad-leaved crops, when used as directed. Phytotoxic to graminaceous crops

Environmental Profile

Ecotoxicology:

• Bees: Non-toxic to bees; LD50 >100 μg/bee.
• Birds: Acute oral LD50 for quail >2000 mg/kg.
• Daphnia: LC50 (48 h) 132 mg/l.
• Fish: LC50 (96 h) for trout 220 mg/l , bluegill sunfish >100 mg/l.

Environmental fate:

• Animals: See Soil/Environment.
• Soil: Rapidly broken down in plants, animals and in the soil by oxidation, conjugation, rearrangement, hydroxylation, and reductive ether-cleavage (Proc. Br. Crop Prot. Conf. - Pests Dis., 1988, 1, 335-341).
• Plant: See Soil/Environment.

Transport Information: Signal Word: CAUTION; Hazard Class: III (Slightly hazardous)

More details can be find in the attached document of FAO.